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OverviewAcromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood. When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism. But in adulthood, a change in height doesn't occur. Instead, the increase in bone size is limited to the bones of your hands, feet and face, and is called acromegaly. Because acromegaly is uncommon and the physical changes occur slowly over many years, the condition sometimes takes a long time to recognize. Untreated, high levels of growth hormone can affect other parts of the body, in addition to your bones. This can lead to serious — sometimes even life-threatening — health problems. But treatment can reduce your risk of complications and significantly improve your symptoms, including the enlargement of your features. SymptomsA common sign of acromegaly is enlarged hands and feet. For example, you may notice that you aren't able to put on rings that used to fit, and that your shoe size has progressively increased. Acromegaly may also cause gradual changes in your face's shape, such as a protruding lower jaw and brow bone, an enlarged nose, thickened lips, and wider spacing between your teeth. Because acromegaly tends to progress slowly, early signs may not be obvious for years. Sometimes, people notice the physical changes only by comparing old photos with newer ones. Overall, acromegaly signs and symptoms tend to vary from one person to another, and may include any of the following:
When to see a doctorIf you have signs and symptoms associated with acromegaly, contact your doctor for an exam. Acromegaly usually develops slowly. Even your family members may not notice the gradual physical changes that occur with this disorder at first. But early diagnosis is important so that you can start getting proper care. Acromegaly can lead to serious health problems if it's not treated. CausesAcromegaly occurs when the pituitary gland produces too much growth hormone (GH) over a long period of time. The pituitary gland is a small gland at the base of your brain, behind the bridge of your nose. It produces GH and a number of other hormones. GH plays an important role in managing your physical growth. When the pituitary gland releases GH into your bloodstream, it triggers your liver to produce a hormone called insulin-like growth factor-1 (IGF-1) — sometimes also called insulin-like growth factor-I, or IGF-I. IGF-1 is what causes your bones and other tissues to grow. Too much GH leads to too much IGF-1, which can cause acromegaly signs, symptoms and complications. In adults, a tumor is the most common cause of too much GH production:
ComplicationsIf left untreated, acromegaly can lead to major health problems. Complications may include:
Early treatment of acromegaly can prevent these complications from developing or becoming worse. Untreated, acromegaly and its complications can lead to premature death. Feb. 16, 2021 What does Hyposecretion of growth hormone cause?GH hypersecretion results in gigantism or acromegaly, a condition associated with significant morbidity and mortality, while GH deficiency results in growth retardation in children and the GH deficiency syndrome in adults.
Which clinical manifestation is found in a patient with deficiency of growth hormone?The symptoms of GH deficiency in adults are often nonspecific. Reported symptoms include low physical and mental energy, decreased muscle strength and exercise tolerance, increased weight or difficulty losing weight, poor memory, emotional instability, impaired sleep, and decreased quality of life.
What are the symptoms and effects of Hyposecretion?breathing rate are increased , while digestive processes are decreased. [No known effects are due to hyposecretion of these, but hypersecretion can caused hypertension, increased blood glucose level , and high heart rate]. The only gland that is both exocrine and endocrine in physiology. through the pancreatic ducts.
Which of the following disorders is a result of Hyposecretion of hormones?So, the correct answer is 'Dwarfism'.
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Which clinical manifestation would be expected in a client with hyposecretion of growth hormone
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