pronounced as (ta kroe' li mus) Show
Tacrolimus injection should only be given under the supervision of a doctor who is experienced in treating people who have had an organ transplant and in prescribing medications that decrease the activity of the immune system. Tacrolimus injection decreases the activity of your immune system. This may increase the risk that you will get a serious infection. If you experience any of the following symptoms, call your doctor immediately: sore throat; cough; fever; extreme tiredness; flu-like symptoms; warm, red, or painful skin; or other signs of infection. When your immune system is not working normally, there may be a greater risk that you will develop cancer, especially lymphoma (a type of cancer that begins in the cells of the immune system). The longer you receive tacrolimus injection or other medications that decrease the activity of the immune system, and the higher your doses of these medications, the more this risk may increase. If you experience any of the following symptoms of lymphoma, call your doctor immediately: swollen lymph nodes in the neck, armpits, or groin; weight loss; fever; night sweats; excessive tiredness or weakness; cough; trouble breathing; chest pain; or pain, swelling, or fullness in the stomach area. Talk to your doctor about the risks of receiving tacrolimus injection. Tacrolimus injection is used along with other medications to prevent rejection (attack of the transplanted organ by the transplant recipient's immune system) in people who have received kidney, liver, or heart transplants. Tacrolimus injection should only be used by people who are unable to take tacrolimus by mouth. Tacrolimus injection is in a class of medications called immunosupressants. It works by decreasing the activity of the immune system to prevent it from attacking the transplanted organ. Tacrolimus injection comes as a solution (liquid) to be injected intravenously (into a vein) by a doctor or nurse in a hospital or medical facility. It is usually given as an ongoing infusion, beginning no sooner than 6 hours after transplant surgery and continuing until tacrolimus can be taken by mouth. A doctor or nurse will watch you closely during the first 30 minutes of your treatment and then will monitor you often so that you can be treated quickly if you have a serious allergic reaction. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Before receiving tacrolimus injection,
Avoid eating grapefruit or drinking grapefruit juice while receiving tacrolimus injection. Tacrolimus injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of the following symptoms, or those mentioned in the IMPORTANT WARNING section, call your doctor immediately:
Tacrolimus injection may cause other side effects. Call your doctor if you have any unusual problems while you are receiving this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Symptoms of overdose may include:
Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to tacrolimus injection. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Which drugs are often administered before and after organ transplant procedure?Immunosuppressants are drugs or medicines that lower the body's ability to reject a transplanted organ. Another term for these drugs is anti-rejection drugs. There are 2 types of immunosuppressants: Induction drugs: Powerful antirejection medicine used at the time of transplant.
What are three main types of antiAlthough there are multiple methods of mixing and matching the above drugs, the most common combination employed by the transplant centers is Tacrolimus, Mycophenolate Mofetil and Prednisone.
What drugs do you have to take after a kidney transplant?Medications After Kidney Transplant. PROGRAF (FK506) – is taken twice a day. ... . CYCLOSPORINE – is taken twice a day. ... . RAPAMUNE (SIROLIMUS) – is taken once a day in the morning. ... . CELLCEPT - is taken two to four times a day. ... . PREDNISONE – is taken for a few days immediately after your transplant.. Why do you need antiAfter an organ transplant, you will need to take immunosuppressant (anti-rejection) drugs. These drugs help prevent your immune system from attacking ("rejecting") the donor organ. Typically, they must be taken for the lifetime of your transplanted organ.
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